Tadalafil

Overview

Tadalafil is a long-acting PDE-5 inhibitor that supports nitric oxide-mediated blood flow by relaxing blood vessels. It is approved for the treatment of erectile dysfunction (ED) and benign prostatic hyperplasia (BPH), and is also being studied for its potential benefits on vascular health, exercise performance, and endothelial function.

Potential Benefits
- Supports healthy blood flow
- May enhance exercise performance and muscle pumps
- May improve exercise tolerance and recovery
- Supports vascular and endothelial health
- Long-lasting effects (up to 36 hours)
- Approved for the treatment of ED and symptoms of BPH

Common Daily Dosing

5 mg once daily

Take at approximately the same time each day
May be taken with or without food

Potential Side Effects
Most side effects are mild and temporary.

Commonly reported:
Headache
Facial flushing
Nasal congestion
Indigestion
Back pain
Muscle aches
Mild dizziness

Precautions

Do not use tadalafil with nitrate medications due to the risk of a significant drop in blood pressure.

Consult a healthcare professional before use if you have cardiovascular disease or are taking blood pressure medications.

Storage

Store in a cool, dry place
Protect from heat, moisture, and direct sunlight

Research Status

Daily tadalafil is an established, approved therapy for erectile dysfunction and benign prostatic hyperplasia. Research is also exploring its potential role in supporting vascular function, endothelial health, and exercise performance in selected populations.